Radical Prostatectomy, External Beam Radiotherapy, or External Beam Radiotherapy With Brachytherapy Boost and Disease Progression and Mortality in Patients With Gleason Score 9-10 Prostate Cancer
نویسندگان
چکیده
منابع مشابه
Salvage External Beam Radiotherapy for Prostate Cancer After Radical Prostatectomy
Prostate cancer is the second most common cause of cancer death in American men, with 192,289 new cases and 27,360 deaths expected in 2009.[1] While radical prostatectomy provides excellent control for clinically localized disease, approximately one-third of patients undergoing surgery will have positive surgical margins and another 9% will have seminal vesicle invasion.[2-5] Around one-third o...
متن کاملMortality after radical prostatectomy or external beam radiotherapy for localized prostate cancer.
BACKGROUND No randomized trials have compared survival outcomes for men with localized prostate cancer (PC) being treated with radical prostatectomy (RP) or external beam radiotherapy (EBRT). The goal of the study, therefore, was to estimate the association of RP (compared with EBRT) with overall and PC mortality. METHODS We analyzed an observational cohort from the population-based Prostate ...
متن کاملCombining external beam radiotherapy with prostate brachytherapy: issues and rationale.
a he optimal treatment for clinically localized prostate cancer remains controversial. For paients with low-risk prostate cancer (Stage T1c2a, Gleason score less than 7, prostate-specific ntigen [PSA] of 10.0 ng/mL), monotherapy with adical prostatectomy, three-dimensional conforal radiotherapy (3D-CRT), intensity-modulated T, or prostate brachytherapy results in similar iochemical relapse-free...
متن کاملBoost in radiotherapy: external beam sunset, brachytherapy sunrise
Radiobiological limitations for dose escalation in external radiotherapy are presented. Biological and clinical concept of brachytherapy boost to increase treatment efficacy is discussed, and different methods are compared. Oncentra Prostate 3D conformal real-time ultrasound-guided brachytherapy is presented as a solution for boost or sole therapy.
متن کاملExternal Beam Radiotherapy in Prostate Cancer
For the first time in their history, the 2 medical organizations most responsible for the treatment of prostate cancer in the United States—the American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA)—have issued a joint guideline, a series of 9 major statements on the use of radiation therapy (either adjuvant or salvage) after prostatectomy. The statements ...
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ژورنال
عنوان ژورنال: JAMA
سال: 2018
ISSN: 0098-7484
DOI: 10.1001/jama.2018.0587